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环状 RGD 多肽系列

名称

序列

 c(RGDfC)

cyclo (Arg-Gly-Asp-d-Phe-Cys)

 c(RGDfE)

cyclo (Arg-Gly-Asp-d-Phe-Glu)

 c(RGDfV)

cyclo (Arg-Gly-Asp-d-Phe-Val)

 c(RGDfK)

cyclo (Arg-Gly-Asp-d-Phe-Lys)

 c(RGDyC)

cyclo (Arg-Gly-Asp-D-Tyr-Cys)

 c(RGDyE))

cyclo (Arg-Gly-Asp-D-Tyr-Glu)

 c(RGDyK)

cyclo (Arg-Gly-Asp-d-Tyr-Lys)

 c(RGDyV)

cyclo (Arg-Gly-Asp-d-Tyr-Val)

 c(RGDFC)

cyclo (Arg-Gly-Asp-Phe-Cys)

 c(RGDFE)

cyclo (Arg-Gly-Asp-Phe-Glu)

 c(RGDFV)

cyclo (Arg-Gly-Asp-Phe-Val)

 c(RGDFK)

cyclo (Arg-Gly-Asp-Phe-Lys)

 c(RGDYC)

cyclo (Arg-Gly-Asp-Tyr-Cys)

 c(RGDYE)

cyclo (Arg-Gly-Asp-Tyr-Glu)

 c(RGDYK)

cyclo (Arg-Gly-Asp-Tyr-Lys)

 c(RGDYV)

cyclo (Arg-Gly-Asp-Tyr-Val)

带有巯基的 RGD 环肽

名称

序列

 cyclo(RGDfK-COCH2SH)

CYCLO(ARG-GLY-ASP-D-Phe-LYS(COCH2SH))

 cyclo(RGDfK)

CYCLO(ARG-GLY-ASP-D-Phe-LYS(mpa))

 cyclo(RGDfK-COCH2CH2SH)

CYCLO(ARG-GLY-ASP-D-Phe-LYS(COCH2CH2SH))

 cyclo(RGDyK-COCH2SH)

CYCLO(ARG-GLY-ASP-D-Tyr-LYS(COCH2SH))

 cyclo(RGDyK)

CYCLO(ARG-GLY-ASP-D-Tyr-LYS(mpa))

 cyclo(RGDyK-COCH2CH2SH)

CYCLO(ARG-GLY-ASP-D-Tyr-LYS(COCH2CH2SH))

带荧光标记的 RGD 环肽

名称

序列

c(RGDFK(Biotin))

cyclo [Arg-Gly-Asp-d-Phe-Lys(Biotin)]

c(RGDfK(Biotin))

cyclo (Arg-Gly-Asp-d-Phe-Lys(Biotin))

c(RGDFK(FITC))

cyclo [Arg-Gly-Asp-d-Phe-Lys(FITC)]

c(RGDfK(FITC))

cyclo (Arg-Gly-Asp-d-Phe-Lys(FITC))

结构复杂的搁骋顿环肽

名称

序列

 E-[c(RGDfK)2]

H-GLU(CYCLO(ARG-GLY-ASP-D-PHE-LYS))2

 E-[c(RGDyK)2]

H-GLU(CYCLO(ARG-GLY-ASP-D-Tyr-LYS))2

线性 RGD 多肽

名称

序列

RGDS

H-Arg-Gly-Asp-Ser-OH

RGES

H-Arg-Gly-Glu-Ser-OH

DRGDS

H-Asp-Arg-Gly-Asp-Ser-OH

DRLDS

H-Asp-Arg-Leu-Asp-Ser-OH

GRADSPK

H-Gly-Arg-Ala-Asp-Ser-Pro-Lys-OH

GRADSP

H-Gly-Arg-Ala-Asp-Ser-Pro-OH

GRDGS

H-Gly-Arg-Asp-Gly-Ser-OH

GRGDS

H-Gly-Arg-Gly-Asp-Ser-OH

GRGDSPK

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

GRGDSP

H-Gly-Arg-Gly-Asp-Ser-Pro-OH

GRGDTP

H-Gly-Arg-Gly-Asp-Thr-Pro-OH

GRGES

H-Gly-Arg-Gly-Glu-Ser-OH

GRGESP

H-Gly-Arg-Gly-Glu-Ser-Pro-OH

GRGETP

H-Gly-Arg-Gly-Glu-Thr-Pro-OH

KGDS

H-Lys-Gly-Asp-Ser-OH

SDGRG

H-Ser-Asp-Gly-Arg-Gly-OH

Ac-DRGDS

Ac-Asp-Arg-Gly-Asp-Ser-OH

Ac-DRLDS

Ac-Asp-Arg-Leu-Asp-Ser-OH

Ac-DRGDS

Ac-Asp-Arg-Gly-Asp-Ser-OH

Ac-DRLDS

Ac-Asp-Arg-Leu-Asp-Ser-OH

环状 RAD 多肽

名称

序列

C(RADfC)

cyclo (Arg-Ala-Asp-d-Phe-Cys)

C(RADfE)

cyclo (Arg-Ala-Asp-d-Phe-Glu)

C(RADfV)

cyclo (Arg-Ala-Asp-d-Phe-Val)

C(RADfK)

cyclo (Arg-Ala-Asp-d-Phe-Lys)

C(RADyC)

cyclo (Arg-Ala-Asp-D-Tyr-Cys)

C(RADyE))

cyclo (Arg-Ala-Asp-D-Tyr-Glu)

C(RADyK)

cyclo (Arg-Ala-Asp-d-Tyr-Lys)

C(RADyV)

cyclo (Arg-Ala-Asp-d-Tyr-Val)

C(RADFC)

cyclo (Arg-Ala-Asp-Phe-Cys)

C(RADFE)

cyclo (Arg-Ala-Asp-Phe-Glu)

C(RADFV)

cyclo (Arg-Ala-Asp-Phe-Val)

C(RADFK)

cyclo (Arg-Ala-Asp-Phe-Lys)

C(RADYC)

cyclo (Arg-Ala-Asp-Tyr-Cys)

C(RADYE)

cyclo (Arg-Ala-Asp-Tyr-Glu)

C(RADYK)

cyclo (Arg-Ala-Asp-Tyr-Lys)

C(RADYV)

cyclo (Arg-Ala-Asp-Tyr-Val)